​Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences, in collaboration with their partners, have developed a novel method for the comprehensive evaluation of probiotic products using a Raman Flow Cytometry (RFC) platform.Published in iMetaOmics, this new method allows for rapid, label-free analysis of identity, viability, an...

​Chinese researchers have developed an advanced, high-throughput single-cell sorting platform that enables direct isolation of living cells with targeted metabolic profiles from large mutant libraries.The technology—now commercialized as FlowRACS 3.0—dramatically shortens the traditionally labor-intensive, colony-by-colony screening process for identifying high-value microbial strains. What ...

​A cutting-edge technology developed by Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences, in collaboration with several renowned institutions, is poised to transform the discovery of microbial species and enzymes with specific in situ metabolic functions.The team’s findings were published in The Innovation on Jan 17.Phylogeny-metabolism dual-direc...

​A team of researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, along with collaborators, have developed a microfluidic system to tackle antimicrobial resistance (AMR). Operating at the picoliter scale, the system condenses billions of bacterial cells into a confined microenvironment, accelerating the experi...

​In the competitive landscape of the yeast fermentation industry, rapid and accurate quality assessment is crucial for optimizing production and enhancing commercial competitiveness.Researchers from Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS) and Tianjin Agricultural College have introduced an innovative approach utilizing single-cell Ra...

Cancer metastasis, a leading cause of cancer-related deaths, involves a complex, multi-stage process. Traditional methods for assessing metastatic potential are often time-consuming and labor-intensive, with limited accessibility to samples.Researchers from Qingdao University and Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences have developed ...

Researchers from the Single-Cell Center at the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, together with collaborators, developed an artificial intelligence-assisted Raman-activated cell sorting (AI-RACS) system. This innovative system automated the isolation and functional analysis of aluminum-tolerant microorganisms (ATMs) from acidic soil, mar...

​Scaling down single-cell reactions to the nanoliter level is critical to minimize the risk of contamination, increase reaction efficiency, and reduce costs.Researchers from the Single-cell Center of the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences have developed a centrifugally driven system for precise manipulation of nanoliter liquids in single...

With the rapid development of genome synthesis and editing technologies, droplet-based single-cell phenotype screening has become increasingly important. However, precise and high-throughput distribution of target droplets into specific macroscopic media for downstream multi-omics analysis remains a technical challenge.Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technolog...

​In response to the escalating challenges posed by the high drug resistance of rapidly growing mycobacteria (RGM), a collaborative team from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences, the Beijing Chest Hospital, and the Qingdao Single-Cell Biotech has achieved a breakthrough in rapid antimicrobial susceptibility testing (AST) of RG...