Raman-activated cell sorting can identify living cells by their chemical fingerprints without fluorescent labels. Yet researchers have faced a trade-off: fast, flowing systems struggle to measure weak Raman signals, while systems that allow longer measurements sort cells slowly. Collecting the selected cells in a large volume can also make subsequent experiments difficult.Researchers at the Qin...

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences, together with Qingdao University of Science and Technology, have discovered a previously unknown marine bacterium that can both fix carbon dioxide and degrade aromatic hydrocarbons. This dual capability could make the bacterium a valuable tool for coastal carbon cycling res...

​Scientists have developed a Raman-activated cell sorting strategy for high-throughput discovery of ethanol-tolerant microorganisms based on their metabolic activity rather than growth.The study, led by the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences, and the COFCO Nutrition & Health Research Institute, was published in Bioresource Technology ...

​Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences, in collaboration with the Shenzhen Institutes of Advanced Technology (SIAT) and Zhonghe Gene Co., Ltd., have proposed an integrated “synthesis-assembly-error correction” paradigm that transforms fragmented DNA synthesis into continuous, automated, high-fidelity pipelines.Publi...

​Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences and Shenzhen Third People's Hospital have developed a Ramanome-based phenotypic platform to improve the efficiency of bacteriophage evaluation for potential clinical use.Their study was published in mLife on May 21.Overview of ramanome-based phage susceptibility test (Imag...

Differences between individual cells play a critical role in mammalian development, immune responses, and disease progression. However, tools capable of capturing, monitoring, and recovering selected cells for downstream analysis are often complex and expensive, limiting their use in many laboratories.To address this need, scientists from the Qingdao Institute of Bioenergy and Bioprocess Techno...

​A collaborative research team led by the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences has developed a new "process ramanomics" platform. This technology transforms industrial fermentation tanks from opaque "black boxes" into transparent, data-rich environments, enabling real-time, data-driven control of biomanufacturing. The study was pu...

​According to a new study published in Analytical Chemistry on March 27, Chinesescientists have developed a rapid and broadly applicable platform for antifungal susceptibility testing, offering a potential new route to faster and more informative diagnosis of invasive fungal infections.AI-assisted multimodal platform for rapid antifungal susceptibility testing  (Image by LIU Yang)The study, ca...

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) andHainan University havedeveloped a workflow for detecting metabolites in single cells of corals in situ. This new platform sheds light on the transfer and recycling of carbon and nitrogen across the coral-Symbiodiniaceae-bacteria consortium. It also produces the firs...

Scientists from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS) and the Tianjin Institute of Industrial Biotechnology (TIB) of CAS, have developed a rapid, high-throughput error-correction platform that significantly improves the accuracy of synthetic DNA. The system, known as engineered MutS-based magnetic bead separation (eMBS), o...