Biography:  

ZHENG Xiaoshan currently serves as a senior engineer of Single-Cell Center at CAS-QIBEBT. She obtained her BSc degree in Chemical Biology in 2010 and her PhD degree in Physical Chemical at Xiamen University in 2015 under the supervision of Prof. Bin Ren on SERS-based living cell study. After serving as a research assistant at State Key Laboratory of Physical Chemistry of Solid Surfaces of Xiamen University, she joined the Department of Spectroscopy and Imaging at the Leibniz Institute of Photonic Technology (Jena, Germany) as a postdoc fellow under the supervision of Prof. Jürgen Popp. She joined Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences as a senior engineer at Single-Cell Center. Her research interests focus on the development of methodology and platform based on Raman and SERS spectroscopy for single cell analysis. She has published over 15 peer-reviewed papers on Chem. Rev., Chem. Soc. Rev., Small, Anal. Chem,. Etc., applied for 3 invention patents, and undertake 3 projects as PI, including young scientist fund of NSFC, Youth Foundation of Shandong Natural Science Foundation, and cooperation fund Shandong Energy Institute.

Research Interests:  

Raman spectroscopy; Surface-enhanced Raman spectroscopy; Nanosensor; bio-sensing; single-cell analysis

Featured Publications :

1. Xiao-Shan Zheng, Cheng Zong, Xin Wang, Bin Ren*. Cell-Penetrating Peptide Conjugated SERS Nanosensor for In Situ Intracellular pH Imaging of Single Living Cells during Cell Cycle. Anal. Chem. 2019, 91 (13):8383-8389.

2. Xiao-Shan Zheng, Izabella Jolan Jahn, Karina Weber, Dana Cialla-May*, Jürgen Popp*. Label-Free SERS in Biological and Biomedical Applications: Recent Progress, Current Challenges and Opportunities. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2018, 197:56-77.

3. Dana Cialla-May, Xiao-Shan Zheng, Karina Weber, Jürgen Popp* (Co-first authors). Recent Progress in Surface-Enhanced Raman Spectroscopy for Biological and Biomedical Applications: From Cells to Clinics. Chem. Soc. Rev. 2017, 46:3945-3961.

4. Xiao-Shan Zheng, Cheng Zong, Meng-Xi Xu, Xiang Wang*, Bin Ren* (Co-first authors)Raman Imaging from Microscopy to Nanoscopy, and to Macroscopy. Small 2015, 11:3395-3406.

5. Xiao-Shan Zheng, Pei Hu, Yan Cui, Cheng Zong, Jia-Min Feng, Xin Wang, Bin Ren*. BSA-Coated Nanoparticles for Improved SERS-Based Intracellular pH Sensing. Anal. Chem. 2014, 86:12250-12257.

6. Xiao-Shan Zheng, Pei Hu, Jin-Hui Zhong, Cheng Zong, Xiang Wang, Bi-Ju Liu, Bin Ren*. Laser Power Dependent Surface-Enhanced Raman Spectroscopic Study of 4-Mecaptopyridine on Uniform Gold Nanoparticle-Assembled Substrates. J. Phys. Chem. C 2014, 118:3750-3757.