郑晓姗 zhengxs@qibebt.ac.cn 高级工程师 单细胞应用示范研究组

教育背景与研究背景

2019年8月至今，中国科学院青岛生物能源与过程研究所，高级工程师

2019年3月至2019年7月，中国科学院青岛生物能源与过程研究所，客座高级工程师

2016年3月至2018年12月，Leibniz Institute of Photonic Technology (Jena, Germany)，博士后，合作导师：Jürgen Popp教授

2015年9月至2016年2月，厦门大学固体表面物理化学国家重点实验室，科研助理 

2010年9月至2015年9月，厦门大学化学系物理化学专业，理学博士，导师：任斌教授

2006年9月至2010年7月，厦门大学化学系化学生物学专业，理学学士

研究方向

拉曼光谱；表面增强拉曼光谱；纳米探针；生物传感；单细胞研究

代表性论文

1. Xiao-Shan Zheng, Cheng Zong, Xin Wang, Bin Ren*. Cell-Penetrating Peptide Conjugated SERS Nanosensor for In Situ Intracellular pH Imaging of Single Living Cells during Cell Cycle. Anal. Chem. 2019, 91 (13):8383-8389. (IF: 6.042)

2. Cheng Zong, Meng-Xi Xu, Li-Jia Xu, Ting Wei, Xin Ma, Xiao-Shan Zheng, Ren Hu, Bin Ren*. Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges. Chem. Rev. 2018, 118:4946-4980. (IF: 52.613)

3. Yuan-Zi Wu, Ye Jiang, Xiao-Shan Zheng, Sha-Sha Jia, Zhi Zhu, Bin Ren*, Hong-Wei Ma*. Facile Fabrication of Microfluidic Surface-Enhanced Raman Scattering Devices via Lift-up Lithography. R. Soc. Open sci. 2018, 5:172034. (IF: 2.504)

4. Xiao-Shan Zheng, Izabella Jolan Jahn, Karina Weber, Dana Cialla-May*, Jürgen Popp*. Label-Free SERS in Biological and Biomedical Applications: Recent Progress, Current Challenges and Opportunities. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2018, 197:56-77. (IF: 2.880)

5. Dana Cialla-May, Xiao-Shan Zheng, Karina Weber, Jürgen Popp* (Co-first authors). Recent Progress in Surface-Enhanced Raman Spectroscopy for Biological and Biomedical Applications: From Cells to Clinics. Chem. Soc. Rev. 2017, 46:3945-3961. (IF: 40.182)

6. Izabella Jolan Jahn, Olga Žukovskaja, Xiao-Shan Zheng, Karina Weber, Thomas Bocklitz, Dana Cialla-May, Jürgen Popp*. Surface-Enhanced Raman Spectroscopy and Microfluidic Platforms: Challenges, Solutions and Potential Applications. Analyst 2017, 142:1022-1047. (IF: 3.864)  

7. Xiao-Shan Zheng, Cheng Zong, Meng-Xi Xu, Xiang Wang*, Bin Ren* (Co-first authors)Raman Imaging from Microscopy to Nanoscopy, and to Macroscopy. Small 2015, 11:3395-3406. (IF: 9.598)  

8. Hai-Xin Lin, Liang Chen, De-Yu Liu, Zhi-Chao Lei, Yu Wang, Xiao-Shan Zheng, Bin Ren, Zhao-Xiong Xie, Galen D. Stucky*, Zhong-Qun Tian*. Constructing Two-Dimensional Nanoparticle Arrays on Layered Materials Inspired by Atomic Epitaxial Growth. J. Am. Chem. Soc. 2015, 137: 2828-2831. (IF: 14.357)

9. Xiao-Shan Zheng, Pei Hu, Yan Cui, Cheng Zong, Jia-Min Feng, Xin Wang, Bin Ren*. BSA-Coated Nanoparticles for Improved SERS-Based Intracellular pH Sensing. Anal. Chem. 2014, 86:12250-12257. (IF: 6.042)

10. Pei Hu, Xiao-Shan Zheng, Cheng Zong, Mao-Hua Li, Li-Ying Zhang, Wei Li*, Bin Ren*. Drop-Coating Deposition and Surface-Enhanced Raman Spectroscopies (DCDRS and SERS) Provide Complementary Information of Whole Human Tears.  J. Raman Spectrosc. 2014, 45:565-573. (IF: 2.879)

11. Xiao-Shan Zheng, Pei Hu, Jin-Hui Zhong, Cheng Zong, Xiang Wang, Bi-Ju Liu, Bin Ren*. Laser Power Dependent Surface-Enhanced Raman Spectroscopic Study of 4-Mecaptopyridine on Uniform Gold Nanoparticle-Assembled Substrates. J. Phys. Chem. C 2014, 118:3750-3757. (IF: 4.484)

12. Li-Jia Xu, Cheng Zong, Xiao-Shan Zheng, Pei Hu, Jia-Min Feng, Bin Ren*. Label-Free Detection of Native Proteins by Surface-Enhanced Raman Spectroscopy Using Iodide-Modified Nanoparticles. Anal. Chem. 2014, 86:2238-2245. (IF: 6.042)

13. Yan Cui, Xiao-Shan Zheng, Bin Ren*, Rui Wang, Jun Zhang, Ning-Shao Xia, Zhong-Qun Tian. Au@organosilica Multifunctional Nanoparticles for the Multimodal Imaging. Chem. Sci. 2011, 2:1463-1469. (IF: 9.063)

著书章节

   宗铖，郑晓姗，许丽佳，胡佩，任斌*，《纳米生物检测》第13章“拉曼光谱和增强拉曼光谱在细胞检测中的应用”，北京：科学出版社，2014

发明专利（按授权日期倒序）

1. 发明名称：可产生三维立体图像的光学显微成像方法

   发明人：郑晓姗，任斌，崔颜，宗铖，刘必聚

   专利号：ZL 2013 1 0129936. X

   授权公告日：2017年3月15日

2. 发明名称：用阴离子修饰纳米粒子增强拉曼光谱的方法

   发明人：任斌，许丽佳，宗铖，郑晓姗，胡佩  

    专利号： ZL 2013 1 0651346. 3

    授权公告日：2017年1月18日