研究队伍

生物信息研究组

 

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刘璐 

liulu@qibebt.ac.cn

助理研究员

生物信息研究组

 

教育与研究背景

 

2019.12-至今  中国科学院青岛生物能源与过程研究所,助理研究员

2017.11-2019.11  中国科学院青岛生物能源与过程研究所,博士后

2015.07-2017.10  中国海洋大学海洋生命学院,博士后

2010.09-2015.06 中国海洋大学医药学院,生药学,医学博士

2007.09-2010.06 福建师范大学生命科学学院,生物化学及分子生物学,理学硕士

2003.09-2007.06 福建师范大学生命科学学院,生物学,理学学士



研究方向

 

微生物组数据库及数据挖掘

数据驱动的微生物科学研究


 

代表性论文


1. Gongchao Jing #, Lu Liu#, Zengbin Wang, Yufeng Zhang, Qian Li, Chunxiao Gao, Meng Zhang, Min Li, Zhenkun Zhang, Xiaohan Liu, Jian Xu, Xiaoquan Su. Microbiome Search Engine 2: a Platform for Taxonomic and Functional Search of Global Microbiomes on the Whole-Microbiome Level. mSystems, 2021, 6(1): e00943-20

2. Lu Liu, Yaoyao Zheng, Changlun Shao, Changyun Wang. Metabolites from marine invertebrate s and their symbiotic microorganisms: molecular diversity discovery, mining, and application. Marine Life Science & Technology, 2019, 1(1): 60-94

3. Lu Liu, Zheng Zhang, Changlun Shao, Changyun Wang. Analysis of the Sequences, Structures and Functions of Product-releasing Enzyme Domains in Fungal Polyketide Synthases. Front Microbiol, 2017, (8): 1685.

4. Lanting Xin#, Lu Liu#, Changlun Shao, Rilei Yu, Fangling Chen, Shijun Yue, Mei Wang, Zhonglong Guo, Yachu Fan, Huashi Guan, Changyun Wang. Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products. Mar Drugs, 2017, 15(7), 217.

5. Lu Liu, Zheng Zhang, Changlun Shao, Jinlan Wang, Hong Bai, Changyun Wang. Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains. Sci Rep, 2015, 5(10463): 112.

6. 刘璐, 邢佩佩,左祖桢,施碧红. 米曲霉葡萄糖淀粉酶基因glaB启动子研究概况.中国生物工程杂志2010. 30(4)116119.

7. Gongchao Jing#, Yufeng Zhang#, Lu Liu, Zengbin Wang, Zheng Sun, Rob Knight, Xiaoquan Su, Jian Xu. A Scale-Free, Fully Connected Global Transition Network Underlies Known Microbiome Diversity. mSystems, 2021. 6(4): p. e0039421.

8. Gongchao Jing, Yufeng Zhang, Wenzhi Cui, Lu Liu, Jian Xu, Xiaoquan Su. Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function. BMC Genomics, 2021. 22(1): p. 9.

9. Mohammadhadi Heidari Baladehi, Maryam Hekmatara, Yuehui He, Yogendra Bhaskar, Zengbin Wang, Lu Liu, Yuetong Ji, Jian Xu. Culture-Free Identification and Metabolic Profiling of Microalgal Single Cells via Ensemble Learning of Ramanomes. Anal Chem, 2021. 93(25): p. 8872-8880.

10. Xiaoquan Su, Gongchao Jing, Zheng Sun, Lu Liu, Zhenjiang Xu, Daniel McDonald, Zengbin Wang, Honglei Wang, Antonio Gonzalez, Yufeng Zhang, Shi Huang, Gavin Huttley, Rob Knight, Jian Xu. Multiple-Disease Detection and Classification across Cohorts via Microbiome Search. mSystems, 2020. 5(2).

11. Gongchao Jing#, Yufeng Zhang#, Ming Yang, Lu Liu, Jian Xu, Xiaoquan Su. Dynamic Meta-Storms enables comprehensive taxonomic and phylogenetic comparison of shotgun metagenomes at the species level. Bioinformatics, 2020. 36(7): p. 2308-2310.

12. Meilin Yu, Yingxin Li, Shivakumar P Banakar, Lu Liu, Changlun Shao, Zhiyong Li, Changyun Wang. New Metabolites From the Co-culture of Marine-Derived Actinomycete Streptomyces rochei MB037 and Fungus Rhinocladiella similis 35. Front Microbiol, 2019. 10: p. 915.

13. Qing Zhao#, An-Na Chen#, Shun-Xin Hu, Qian Liu, Min Chen, Lu Liu, Chang-Lun Shao, Xue-Xi Tang, Chang-Yun Wang. Microalgal Microscale Model for Microalgal Growth Inhibition Evaluation of Marine Natural Products. Sci Rep, 2018. 8(1): p. 10541.

14. 孟菲菲,司君利,刘璐,崔京远,亓玉琴,吕梅. 长链非编码RNA MEG3 在胃癌中的表达及其与预后的关系. 中国肿瘤临床2016. 43(15): 659662.


 

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