研究队伍

微流控系统研究组

葛安乐

geal@qibebt.ac.cn

助理研究员

微流控系统研究组


教育与研究背景

 

2011年于潍坊医学院获理学学士学位,2017年于华中科技大学获工学博士学位,同年加入中国科学院青岛生物能源与过程研究所。自2017年起致力于微流控液滴芯片与质谱接口耦合方法学研究,近期开始着力推进新冠病毒的快速检测。研究成果在Biosensors & Bioelectronics Lab on a chipSensors & Actuators B: Chemical 等国际一流杂志发表7篇文章,申请/授权专利4项,制定国家标准1项。主持项目包括国家自然科学基金青年基金、山东省博士基金等。


研究方向

 

微流控芯片,液滴分选与液滴点样,病原菌快检


代表性论文


  1. Anle Ge#, Fengyi Liu#, Xindong Teng#, Chaojie Cui, Fei Wu, Wenjing Liu, Yang Liu, Xiaoguang Chen*, Jian Xu, Bo Ma*, A Palm Germ-Radar (PaGeR) for rapid and simple COVID-19 detection by reverse transcription loop-mediated isothermal amplification (RT-LAMP). Biosensors & Bioelectronics, 2022: 200: 113925.

  2. Anle Ge#, Liang Hu#, JiaXing Fan, Minghai Ge, Xixian Wang, Shanshan Wang, Xiaojun Feng, Wei Du*, Bi-Feng Liu*, A low-cost microfluidic platform coupled with light emitting diode for optogenetic analysis of neuronal response in C. elegans, Talanta, 2021, 223: 121646

  3. Anle Ge#, Xixian Wang#, Minghai Ge, Liang Hu, Xiaojun Feng, Wei Du*, Bi-feng Liu*, Profile analysis of C. elegans rheotaxis behavior using a microfluidic device. Lab on a Chip, 2019, 19: 475-483

  4. Anle Ge, Liang Hu, Xixian Wang, Jinchi Zhu, Xiaojun Feng, Wei Du*, Bi-Feng Liu, Logarithmic bacterial gradient chip for analyzing the effects of dietary restriction on C. elegans growth, Sensors & Actuators B: Chemical, 2018, 255: 735~744

  5. Liang Hu#, Anle Ge#, Xixian Wang, Shanshan Wang, Xinpei Yue, Jie Wang, Xiaojun Feng, Wei Du*, Bi-Feng Liu*, Real-time monitoring of immune responses under pathogen invasion and drug interference by integrated microfluidic device coupled with worm-based biosensor, Biosensors & Bioelectronics, 2018, 110: 233-238 (co-first author)

  6. Xixian Wang#, Anle Ge#, Liang Hu, Xiaojun Feng, Wei Du*, Bi-Feng Liu*, A microfluidic microfilter chip driven by electrotaxis and fluid flow for size-dependent C. elegans sorting with high purity and efficiency, Sensors & Actuators B: Chemical, 2018, 260: 311~319 (co-first author)

  7. Xixian Wang#, Anle Ge#, Liang Hu, Xiaojun Feng, Wei Du*, Bi-Feng Liu, A novel on-chip immobilization strategy for imaging analysis of neuronal response to gas cues in C. elegans, Sensors and Actuators B: Chemical, 2017, 244: 1152~1159 (co-first author)

  8. Mengzhe Li, Anle Ge, Mengmeng Liu, Bo Ma, Cuiping Ma, and Chao Shi. "A fully integrated hand-powered centrifugal microfluidic platform for ultra-simple and non-instrumental nucleic acid detection." Talanta. 2020, 219: 121221

  9. Liang Hu, Anle Ge, Xixian Wang, Shanshan Wang, Yue Gao, Xiaojun Feng, Wei Du and Bi-Feng Liu. An on-demand gas segmented flow generator with high spatiotemporal resolution for in vivo analysis of neuronal response in C. elegans, Lab on a Chip, 2016, 16: 4020-4027

  10. Yu Wang#, Xixian Wang#, Anle Ge, Liang Hu, Wei Du, and Bi-Feng Liu. A dual-stimulation strategy in a micro-chip for the investigation of mechanical associative learning behavior of C. elegans. Talanta, 2020, 215: 120900

  11. Xixian Wang#, Rui Hu#, Anle Ge, Liang Hu, Shanshan Wang, Xiaojun Feng, Wei Du, Bi-Feng Liu. Highly efficient microfluidic sorting device for synchronizing developmental stages of C. elegans based on deflecting electrotaxis, Lab on a Chip, 2015, 15: 2513-2521

  12. Liang Hu#, Jinjuan Ye#, Haowei Tan, Anle Ge, Lichun Tang, Xiaojun Feng, Wei Du, Bi-Feng Liu. Quantitative analysis of Caenorhabditis elegans chemotaxis using a microfluidic device, Analytica Chimica Acta, 2015, 887: 155-162

  13. Xiankai Li, Mingjie Li, Qinghui Shou, Li Zhou, Anle Ge, Danfeng Pei, and Chaoxu Li. Liquid Metal Initiator of Ring‐Opening Polymerization: Self‐Capsulation into Thermal/Photomoldable Powder for Multifunctional Composites. Advanced Materials. 2020, 32 (43): 20035531

  14. Xing Zhao, Gaozhi Ou, Mengcheng Lei, Yang Zhang, Lina Li, Anle Ge, Yachao Wang, Yiwei Li, and Bi-Feng Liu. Rapid generation of hybrid biochemical/mechanical cues in heterogeneous droplets for high-throughput screening of cellular responses. Lab on a Chip, 2021, 21, 2691-2701

  15. Ma, Peng#, Shanshan Wang#, Ruixue Guan, Liang Hu, Xixian Wang, Anle Ge, Jinchi Zhu, Wei Du, and Bi-Feng Liu. An integrated microfluidic device for studying controllable gas embolism induced cellular responses. Talanta 2020, 208: 120484.


地址: 山东省青岛市崂山区松岭路189号
Email:singlecell@qibebt.ac.cn

联系电话/传真:86-532-80662653/2654

Copy © 2013 青岛生物能源与过程研究所单细胞研究中心 保留所有权利

鲁ICP备12003199号-3 鲁公网安备37021202001256