刘璐  liulu@qibebt.ac.cn 助理研究员 生物信息研究组

教育与研究背景

2019.12-至今  中国科学院青岛生物能源与过程研究所，助理研究员

2017.11-2019.11  中国科学院青岛生物能源与过程研究所，博士后

2015.07-2017.10  中国海洋大学海洋生命学院，博士后

2010.09-2015.06 中国海洋大学医药学院，生药学，医学博士

2007.09-2010.06 福建师范大学生命科学学院，生物化学及分子生物学，理学硕士

2003.09-2007.06 福建师范大学生命科学学院，生物学，理学学士

研究方向

微生物组数据库及数据挖掘

数据驱动的微生物科学研究

代表性论文

1. Gongchao Jing ^#, Lu Liu^#, Zengbin Wang, Yufeng Zhang, Qian Li, Chunxiao Gao, Meng Zhang, Min Li, Zhenkun Zhang, Xiaohan Liu, Jian Xu^﹡, Xiaoquan Su^﹡. Microbiome Search Engine 2: a Platform for Taxonomic and Functional Search of Global Microbiomes on the Whole-Microbiome Level. mSystems, 2021, 6(1): e00943-20

2. Lu Liu, Yaoyao Zheng, Changlun Shao^﹡, Changyun Wang^﹡. Metabolites from marine invertebrate s and their symbiotic microorganisms: molecular diversity discovery, mining, and application. Marine Life Science & Technology, 2019, 1(1): 60-94

3. Lu Liu, Zheng Zhang^﹡, Changlun Shao, Changyun Wang^﹡. Analysis of the Sequences, Structures and Functions of Product-releasing Enzyme Domains in Fungal Polyketide Synthases. Front Microbiol, 2017, (8): 1685.

4. Lanting Xin^#, Lu Liu^#, Changlun Shao, Rilei Yu, Fangling Chen, Shijun Yue, Mei Wang, Zhonglong Guo, Yachu Fan, Huashi Guan^﹡, Changyun Wang^﹡. Discovery of DNA Topoisomerase I Inhibitors with Low-Cytotoxicity Based on Virtual Screening from Natural Products. Mar Drugs, 2017, 15(7), 217.

5. Lu Liu, Zheng Zhang^﹡, Changlun Shao, Jinlan Wang, Hong Bai, Changyun Wang^﹡. Bioinformatical analysis of the sequences, structures and functions of fungal polyketide synthase product template domains. Sci Rep, 2015, 5(10463): 1−12.

6. 刘璐, 邢佩佩，左祖桢，施碧红^﹡. 米曲霉葡萄糖淀粉酶基因glaB启动子研究概况.中国生物工程杂志，2010. 30(4)：116−119.

7. Gongchao Jing^#, Yufeng Zhang^#, Lu Liu, Zengbin Wang, Zheng Sun, Rob Knight, Xiaoquan Su^﹡, Jian Xu^﹡. A Scale-Free, Fully Connected Global Transition Network Underlies Known Microbiome Diversity. mSystems, 2021. 6(4): p. e0039421.

8. Gongchao Jing, Yufeng Zhang, Wenzhi Cui, Lu Liu, Jian Xu, Xiaoquan Su^﹡. Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function. BMC Genomics, 2021. 22(1): p. 9.

9. Mohammadhadi Heidari Baladehi, Maryam Hekmatara, Yuehui He, Yogendra Bhaskar, Zengbin Wang, Lu Liu, Yuetong Ji, Jian Xu. Culture-Free Identification and Metabolic Profiling of Microalgal Single Cells via Ensemble Learning of Ramanomes. Anal Chem, 2021. 93(25): p. 8872-8880.

10. Xiaoquan Su^﹡, Gongchao Jing, Zheng Sun, Lu Liu, Zhenjiang Xu, Daniel McDonald, Zengbin Wang, Honglei Wang, Antonio Gonzalez, Yufeng Zhang, Shi Huang, Gavin Huttley, Rob Knight^﹡, Jian Xu^﹡. Multiple-Disease Detection and Classification across Cohorts via Microbiome Search. mSystems, 2020. 5(2).

11. Gongchao Jing^#, Yufeng Zhang^#, Ming Yang, Lu Liu, Jian Xu, Xiaoquan Su^﹡. Dynamic Meta-Storms enables comprehensive taxonomic and phylogenetic comparison of shotgun metagenomes at the species level. Bioinformatics, 2020. 36(7): p. 2308-2310.

12. Meilin Yu, Yingxin Li, Shivakumar P Banakar, Lu Liu, Changlun Shao, Zhiyong Li^﹡, Changyun Wang^﹡. New Metabolites From the Co-culture of Marine-Derived Actinomycete Streptomyces rochei MB037 and Fungus Rhinocladiella similis 35. Front Microbiol, 2019. 10: p. 915.

13. Qing Zhao^#, An-Na Chen^#, Shun-Xin Hu, Qian Liu, Min Chen, Lu Liu, Chang-Lun Shao^﹡, Xue-Xi Tang^﹡, Chang-Yun Wang^﹡. Microalgal Microscale Model for Microalgal Growth Inhibition Evaluation of Marine Natural Products. Sci Rep, 2018. 8(1): p. 10541.

14. 孟菲菲，司君利，刘璐，崔京远，亓玉琴^﹡，吕梅. 长链非编码RNA MEG3 在胃癌中的表达及其与预后的关系. 中国肿瘤临床，2016. 43(15): 659−662.